Artículos FC IFIS

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Browsing Artículos FC IFIS by Author "Narciso Antonio Villar Goris"

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    Efficacy of direct current generated by multiple electrode arrays on F311 mammary carcinoma: experiment and mathematical modeling
    (2020) Narciso Antonio Villar Goris
    The modified Gompertz equation has been proposed to fit experimental data for direct current treated tumors when multiple-straight needle electrodes are individually inserted into the base perpendicular to the tumor long axis. The aim of this work is to evaluate the efficacy of direct current generated by multiple-electrode arrays on F3II mammary carcinoma that grow in the male and female BALB/c/Cenp mice, when multiple-straight needle electrodes and multiple-pairs of electrodes are inserted in the tumor.
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    Grafeno, producción, caracterización y aplicaciones
    (2023) José Luis García Bello; Narciso Antonio Villar Goris; Taira Batista Luna
    Entre los compuestos basados en carbono, se encuentra el grafeno. Este es un material excepcional, tanto desde el punto de vista de la investigación en física fundamental, como desde el punto de vista de sus aplicaciones prácticas. El grafeno ocupa un lugar destacado en la ciencia, y las diferentes investigaciones realizadas están permitiendo abrir nuevas vías al desarrollo de materiales funcionales. En este trabajo, se analiza la estructura de este interesante compuesto. También, se describen las propiedades químicas, eléctricas, mecánicas y térmicas. Por otro lado, analizan los métodos empleados para su síntesis y las técnicas utilizadas para su caracterización. Por último, se aborda su importancia en la creación de nuevos materiales con propiedades mejoradas; asícomo sus diversas aplicaciones en diferentes áreas de la ciencia y la tecnología. Estas propiedades, también hacen que el grafeno sea el material ideal para ser aplicado, no solo en el campo de la electrónica; sino también la medicina, farmacéutica, energía, entre otras. Dichas propiedades, se verán ampliamente beneficiadas de este novedoso nanomaterial bidimensional
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    Simulations of surface charge density changes during the untreated solid tumour growth
    (2022-11-30) Narciso Antonio Villar Goris
    Understanding untreated tumour growth kinetics and its intrinsic behaviour is interesting and intriguing. The aim of this study is to propose an approximate analytical expression that allows us to simulate changes in surface charge density at the cancer-surrounding healthy tissue interface during the untreated solid tumour growth. For this, the Gompertz and Poisson equations are used. Simulations reveal that the unperturbed solid tumour growth is closely related to changes in the surface charge density over time between the tumour and the surrounding healthy tissue. Furthermore, the unperturbed solid tumour growth is governed by temporal changes in this surface charge density. It is concluded that results corroborate the correspondence between the electrical and physiological parameters in the untreated cancer, which may have an essential role in its growth, progression, metastasis and protection against immune system attack and anti-cancer therapies. In addition, the knowledge of surface charge density changes at the cancer-surrounding healthy tissue interface may be relevant when redesigning the molecules in chemotherapy and immunotherapy taking into account their polarities. This can also be true in the design of completely novel therapies.
  • Item
    Simulations of Surface charge density changes during the untreated solid tumour growth
    (2022-11-30) Narciso Antonio Villar Goris
    Understanding untreated tumour growth kinetics and its intrinsic behaviour is interesting and intriguing. The aim of this study is to propose an approximate analytical expression that allows us to simulate changes in surface charge density at the cancer-surrounding healthy tissue interface during the untreated solid tumour growth. For this, the Gompertz and Poisson equations are used. Simulations reveal that the unperturbed solid tumour growth is closely related to changes in the surface charge density over time between the tumour and the surrounding healthy tissue. Furthermore, the unperturbed solid tumour growth is governed by temporal changes in this surface charge density. It is concluded that results corroborate the correspondence between the electrical and physiological parameters in the untreated cancer, which may have an essential role in its growth, progression, metastasis and protection against immune system attack and anti-cancer therapies. In addition, the knowledge of surface charge density changes at the cancer-surrounding healthy tissue interface may be relevant when redesigning the molecules in chemotherapy and immunotherapy taking into account their polarities. This can also be true in the design of completely novel therapies.