Artículos FCS INSIS

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Browsing Artículos FCS INSIS by Author "Manuel Colomé"

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    Letalidad por dengue y desigualdades en la Región las Américas entre el 2014 y el 2023
    (2024-12-20) Manuel Colomé
    Objetivo. Evaluar las diferencias en la letalidad del dengue entre las distintas subregiones de las Américas en el período 2014-2023 y explorar su relación con el índice de desarrollo humano (IDH) de cada región. Método. Estudio ecológico longitudinal realizado a partir de datos de acceso libre de cada país, que se agruparon en las subregiones correspondientes para calcular los distintos indicadores. Además, se realizó una regresión lineal entre la letalidad media en cada región y el IDH regional ponderado. Resultados. Existen grandes diferencias en la letalidad por dengue según la subregión y una variabilidad considerable según el año. Estas diferencias de letalidad no están directamente correlacionadas con la incidencia registrada en cada región. El IDH regional muestra una estrecha relación con la letalidad: un mayor IDH se asocia generalmente a una menor letalidad. Conclusiones. Las diferencias subregionales de letalidad y su relación con el nivel de desarrollo señalan que la estrategia de control del dengue debe ser diseñada desde una perspectiva amplia y multifactorial.
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    Road traffic injuries and fatalities in Dominican Republic, 2017 -2021: a neglected epidemic
    (2024-11-13) Manuel Colomé
    "Background: Road traffic injuries and fatalities are a major public health concern in the Dominican Republic. Despite efforts to improve road safety, the number of deaths and injuries remains high. This study aims to analyze the epidemiology of road traffic fatalities and injuries in the country from 2017 to 2021. Methods: Data on road traffic injuries and fatalities were collected from the National Police Department, the Ministry of Health, and hospitals across the country. Descriptive statistics were used to analyze the data, including age, sex, and type of vehicle involved in the crash. Results: During the study period, there were 513,629 road traffic injuries and 14,692 fatalities in the Dominican Republic. The majority of those involved in crashes were males aged between 20-39 years old. Motorcycles were the most common type of vehicle involved in crashes. There was a significant reduction in the number of injuries and deaths in 2020, likely due to mobility restrictions during the COVID-19 pandemic. Conclusions: Road traffic injuries and fatalities in the Dominican Republic are a neglected epidemic that requires immediate attention. Improving road safety measures, targeting high-risk groups, and implementing safer pedestrian infrastructure are essential to reducing the number of injuries and deaths on the country's roads."
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    Spinal muscular atrophy type 1 in the Caribbean: the first case report from the Dominican Republic
    (2025-01-08) Manuel Colomé
    Spinal muscular atrophy (SMA) is a progressive genetic neuromuscular condition affecting spinal motor neurons. The underlying cause of SMA is deletions or mutations in the SMN gene. It is classified into five variants based on age and clinical manifestations of the patient. In this report, we present the case discovery of a four-month-old male patient with SMA type 1, presenting with generalized hypotonia and regression of acquired neurodevelopmental milestones. Our study aims to illustrate, through a case report, the clinical analysis, therapeutic interventions, and progression until the patient’s demise. This aims to share the challenges in managing such patients and the strategies employed in their care plan. By documenting this case, our goal is to contribute to the understanding of SMA type 1 and emphasize the ongoing need for learning effective care strategies.